Similar to how I have it running in terms of vsync.
Yeah all my monitors are set to a div of 60 already and obviously tested everything running at a flat 60hz too.
Thought I fixed it myself a few weeks back by installing AVG and using Spybot Anti beacon / Win10APrivacy but it reared it's head again not long after.
I did try the test build, no luck there.
Purchased a 4k60pro mk2 to see if it was purely a NDI issue my end, still no luck.
Out of curiosity I installed a win 8.1 build on my streaming pc and loaded that up, tested out NDI and it was 99% smooth, there was a slight blip here and there but a ton better than results I'm getting with 2 x Win 10 setup. But 4k60pro doesn't work on Win 8.1 so I'm either left with an expensive pci-e brick sitting on my desk or I roll back to Win 8.1 on my streaming pc to get a somewhat decent looking output.
I agree it's something to do with frame pacing/timing or something along those lines.
This is exactly what I'm seeing in recordings streams.
www.testufo.com/stutter#demo=slowdowns&foreground=ffffff&background=000000&pps=720
like something is halving the refresh rate in OBS intermittantly, it'll run perfectly for around 20-30 secs, then 5 secs of slowdown then back to normal. It's not exactly timed, sometimes it can go 2 mins + without any slowdown, or it can be instant. Hard to pin point it.